Clinoril (sulindac) is a nonsteroidal anti-inflammatory drug (NSAID) used to help alleviate pain and inflammation in a range of chronic and acute conditions. The medication is relatively unique among NSAIDs in that it is less likely than most of its competitors to cause gastric side effects.

Patients commonly buy Clinoril to help alleviate symptoms from:

• Osteoarthritis
• Rheumatoid arthritis
• Ankylosing spondylitis
• Acute gouty arthritis
• Spinal pain or spasms
• Subacromial bursitis
• Supraspinatus tendinitis
• Severe menstrual cramps

Interestingly the medication also has some cancer-fighting properties. Patients with precancerous colon polyps or lesions may be given a prescription to buy Clinoril to inhibit further growth; use in more advanced stages of cancer are still largely experimental, but the medication does show some promise. There is also ongoing research into using Clinoril to treat symptoms of Alzheimer's disease.

Note that patients who have experienced allergic reactions or other serious adverse effects from other NSAIDs, such as aspirin or ibuprofen, are at increased risk of experiencing similar reactions to Clinoril (or any other NSAID).

Treatment Guidelines

Used to manage pain or inflammation treatment with Clinoril is largely similar in most respects regardless of the condition being treated, but can vary tremendously when it comes to duration of treatment. The medication is administered by tablet, typically taken twice per day with food.

In otherwise healthy adults:

• Treatment typically starts with 100 to 150 mg, taken twice per day.
• If needed dosage can be increased to 200 mg taken twice per day.
• Do not exceed a total of 400 mg per day.

Some pain relief should be experienced with the first dose, though it may take a few days of treatment for full relief, particularly when severe inflammation is involved. Most patients experience maximum benefit within 7 days of treatment, and in many cases treatment may then end.

In more severe, chronic conditions treatment may continue for much longer, sometimes for years. In long-term use it is rare that patients take the maximum dose; 50 to 100 mg twice per day is far more common. Long-term use at high doses greatly increases risk of serious complications.

Patients who buy Clinoril to treat arthritic conditions often experience, in addition to pain relief, improved joint mobility, range of motion, and general joint function. It also reduces the duration of exercise-induced stiffness.

Warnings before Use

In most respects side effects associated with Clinoril are similar to those experienced with any other NSAID; typically mild and not cause for concern. However, all NSAIDs are also associated with more serious complications, though rare:

• High blood pressure
• Stroke
• Heart attack
• Anemia
• Bleeding or ulcers in the stomach or intestine
• Liver damage
• Kidney damage

Patients with a history of ulcers, gastric issues, high blood pressure, and any cardiovascular issues are at increased risk of experiencing the above complications. Discuss risks and warning signs with a doctor before using Clinoril or any NSAID.

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